Sustained Release of Minocycline Hydrochloride from Biomaterials
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چکیده
منابع مشابه
Sustained Release of Minocycline Hydrochloride from Biomaterials
Minocycline Hydrochloride (MH) is a second-generation, semisynthetic tetracycline antibiotic derivative (Figure 1). It blocks the association of aminoacyl-tRNA with the bacterial ribosome and thus inhibits the bacterial protein synthesis. Independent of its antibacterial property, MH also exhibits potent anti-inflammatory effects, which makes it a promising drug candidate to combat implant-asso...
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An emulsion solvent evaporation method was employed to prepare microspheres of ropinirole hydrochloride, a highly water soluble drug, by using ethylcellulose and PEG with the help of 32 full factorial design. The microspheres were made by incorporating the drug in a polar organic solvent, which was emulsified using liquid paraffin as an external oil phase. Effects of various process parameters ...
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Infection and inflammation are common complications that seriously affect the functionality and longevity of implanted medical implants. Systemic administration of antibiotics and anti-inflammatory drugs often cannot achieve sufficient local concentration to be effective, and elicits serious side effects. Local delivery of therapeutics from drug-eluting coatings presents a promising solution. H...
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An oral suspension could a suitable dosage form for the geriatric patients. The calcium alginate coated ion exchange resinate of propranolol hydrochloride were prepared using Amberlite IR-120 by solvent evaporation. Microcapsules of propranolol hydrochloride resinate were prepared by solvent evaporation technique,the suspensions were prepared by using deionised water as the vehicle. Methy...
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ژورنال
عنوان ژورنال: Journal of Nanomedicine & Biotherapeutic Discovery
سال: 2016
ISSN: 2155-983X
DOI: 10.4172/2155-983x.1000e142